Hello Leontine,
I absolutely LOVE this concept! Your characters and design are super cute and very appealing. And the setting is awesome. I look forward to seeing the finished piece.
A few small things.
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Watch out for tangents. This can flatten the piece. There is a lot going on in the area between the stuffed mouse and the girl's face.
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I like all the small details in the scene, have you thought about spreading some of the items out? I sketched out a very rough idea of what I was thinking that may give the image a little more breathing room.
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In my rough sketch I moved the stuffed animal on the table, but you could still keep the stuffed animal in her hands but make him not so close to her cheek, or you could have him laying on the corner of the bed if you wanted to fill that space. Then on that small desk in the foreground you could have the balloon connected to a weight sitting on it or even a small vase with a flower?
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I think it is okay to have more diverse shapes, meaning having items be from small, medium, to large. Like playing with the size of the balloon or posters in the back? I like how everything is blown up bigger but it might be worth trying.
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Where will the title of the book be going? Will it be going above the image?
Overall very lovely work. Keep it up!